Keywords: growing rabbits, Saccharomyces cerevisiae, fattening performance, meta-analysis
A study was conducted to determine the effect of Saccharomyces cerevisiae supplementation in the diet of growing rabbits on their mortality, fattening performance and feed conversion rates.
In a pooled analysis, supplementation of Saccharomyces cerevisiae to the diet of growing rabbits caused a significant increase in final weight by 132.24 g (non-standardized average difference). According to the obtained data, there is a systematic error associated with publication bias (Egger’s test, p =<0.001) and high heterogeneity between studies (I2 = 92.9 %, p<0.001). The results of the Q-test (χ2=282.733) and its p-level (<0.001) indicate the occurrence of statistically significant heterogeneity and the null hypothesis which states that all studies share a common effect size was rejected. The effect of Saccharomyces cerevisiae administration was not characterized by statistically significant variation in the genetic subgroups of rabbits (test for subgroup differences: p=0.759). In parallel there was a statistically significant variation in subgroups of SC dose (test for subgroup differences: p=0.04). When a higher concentration of Saccharomyces cerevisiae was used, the average final weight in the experimental group was 209.23 g higher than the final weight in the control group. When a lower concentration of SC was used, the average final weight in experiment was more than the control by 93.38 g.
In own researches Saccharomyces cerevisiae (MUGL 39885, 0.01% – 15 billion cell per gram) was added to the feed for the experimental group before granulation. After 37 days of fattening, the control group reached an average weight of 2230 g, whereas the weight for the experimental group was 2608 g, probably due to the better FCR in the experimental group. Both mentioned differences were significant. Whereas the daily feed intake did not differ in the studied groups. Comparison of the rabbit survival in each group showed no significant difference for the one-sided t-criterion (p=0.097).
Therefore, the usage of feed with Saccharomyces cerevisiae additive affects the results conceding rabbits fattening. Experimental group obtained the statistically significant best average final weight, daily gain and feed conversion ratio in the same raising conditions. It confirms the results obtained from the meta-analysis. At the same time, there is no statistically proven change in feed intake between groups, and that is a promising and important economic and ecological result.
- Wang, H.; Long, W.; Chadwick, D.; Zhang, X.; Zhang, S.; Piao, X.; & Hou, Y. (2022). Dietary Acidifiers as an Alternative to Antibiotics for Promoting Pig Growth Performance: A Systematic Review and Meta-Analysis. Animal Feed Science and Technology, 289, 115320. https://doi.org/10.1016/j.anifeedsci.2022.115320.
- Carabaño, R., Badiola, I., Licois, D., & Gidenne, T. (2006). The Digestive Ecosystem and Its Control through Nutritional or Feeding Strategies. In: Maertens L., Coudert P., editors. Recent Advances in Rabbit Sciences. Melle, Belgium, 211–227.
- Vilà, B., Esteve-Garcia, E., & Brufau, J. (2010). Probiotic Micro-Organisms: 100 Years of Innovation and Efficacy; Modes of Action. World’s Poult. Sci. J., 66, 369–380. https://doi.org/10.1017/S0043933910000474.
- Havenaar, R., ten Brink, B., & Huis, J. H. J. (1992). Probiotics. Springer; Berlin/Heidelberg, Germany: Selection of Strains for Probiotic Use, 209–224.
- Misiukiewicz, A., Gao, M., Filipiak, W., Cieslak, A., Patra, A. K., & Szumacher-Strabel, M. (2021). Review: Methanogens and methane production in the digestive systems of nonruminant farm animals. Animal, 15(1), 100060. https://doi.org/10.1016/j.animal.2020.100060
- Chaudhary, L. C., Singh, R., Kamra, D. N., & Pathak, N. N. (1995). Effect of oral administration of yeast (Saccharomyces Cerevisiae) on digestibility and growth performance of rabbits fed diets of different fibre content. World Rabbit Science, 3(1), 15-18. https://doi.org/10.4995/wrs.1995.235
- Korkh, O. V., Platonova, N. P., Aksonov, Іe. O., Petrash, V. S., & Smetana, O. I. (2021). Pokaznyky miasnoi produktyvnosti vidhodivelnoho molodniaku kroliv za vykorystannia probiotyka [Indicators of meat productivity of fattening young rabbits using probiotics]. Naukovo-tekhnichnyi biuleten Instytutu tvarynnytstva NAAN –Scientific and Technical Bulletin of the Institute of Animal Science of the National Academy of Agrarian Science of Ukraine. Kharkiv, 126, 52–61. https://doi.org/10.32900/2312-8402-2021-126-52-62 [in Ukrainian]. http://animal.kharkov.ua/index.php/component/content/article/2-uncategorised/640-ntb126-8
- Gidenne, T, & Maertens, L. (2016). Feed efficiency in rabbit production: Nutritional, technico-economical and environmental aspects. In: 11. World Rabbit Congress. Proceedings World Rabbit Congress. WRSA. Accessed July 15. https://hal.archives-ouvertes.fr/hal-02046863.
- Higgins, J. P. T, Thomas, J., Chandler, J., Cumpston, M., Li, T., Page, M.J., & Welch, V. A. (editors) (2022). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane. Available from www.training.cochrane.org/handbook.
- Jerome, N., Mousset, J. L., Lebas, F., & Robart, P. (1996). Effect of diet supplementation with oxytetracycline combi ned or not with different feed-additives on fattening performance in the rabbit. 6th World Rabbit Congress, Toulouse, France, 9-12/07/1996. 1. 205-210.
- Onifade, A. A., Obiyan, R. I., Onipede, E., Adejumo, D. O., Abu, O. A., & Babatunde, G. M. (1999). Assessment of the effects of supplementing rabbit diets with a culture of Saccharomyces cerevisiae using growth performance, blood composition and clinical enzyme activities. Animal Feed Science and Technology, 77(1-2), 25-32. https://doi.org/10.1016/S0377-8401(98)00244-2
- Lambertini, L., Vignola, G., Beone, G. M., Zaghini, G., & Formigoni, A. (2004). Effects of chromium yeast supplementation on growth performances and meat quality in rabbits. World Rabbit Science, 12(1), 33-47. https://doi.org/10.4995/wrs.2004.582
- Kimsé, M., Bayourthe, C., Monteils, V., et al. (2012). Live yeast stability in rabbit digestive tract: Consequences on the caecal ecosystem, digestion, growth and digestive health. Animal Feed Science and Technology, 173, 235-243. https://doi.org/10.1016/j.anifeedsci.2012.01.012
- Rotolo, L., Gai, F., Peiretti, P. G., Ortoffi, M., Zoccarato, I., & Gasco, L. (2014). Live yeast (Saccharomyces cerevisiae var. boulardii) supplementation in fattening rabbit diet: Effect on productive performance and meat quality. Livestock Science, 162, 178-184. https://doi.org/10.1016/j.livsci.2014.01.022
- Belhassen, T., Bonai, A., Gerencsér, Z., et al. (2016). Effect of diet supplementation with live yeast Saccharomyces cerevisiae on growth performance, caecal ecosystem and health of growing rabbits. World Rabbit Science, 24 (3), 191-200. https://doi.org/10.4995/wrs.2016.3991
- El-Kelawy, H., & El-Kelawy, M. (2016). Impact of dietary supplementation with multi enzyme and/or probiotic on growth performance, nutrients digestibility and blood constituents of growing rabbits. Egyptian Journal of Nutrition and Feeds, 19(2), 313-323. https://doi.org/10.21608/ejnf.2016.74913
- Ayyat, M. S., Al-Sagheer, A. A., Abd, El-Latif, K. M., & Khalil, B. A. (2018). Organic Selenium, Probiotics, and Prebiotics Effects on Growth, Blood Biochemistry, and Carcass Traits of Growing Rabbits During Summer and Winter Seasons. Biol Trace Elem Res., 186(1), 162-173. https://doi.org/10.1007/s12011-018-1293-2
- Awad, A., Abd Elhamid, A. E., Azoz, A. B., & Elthawy, W. (2019). Effect of addition of Saccharomyces cerevisiae and/ or sodium butyrate on growth performance and blood biochemicals in growing rabbits. Egyptian Journal of Rabbit Science., 29 (2), 171-195. https://doi.org/10.21608/ejrs.2019.84223
- Abdel-Aziz Elsawy, B., Ahmed, A., Elbadwy, Y., & Elsyed, I. (2021). Impact of Saccharomyces Cerevisiae Boulardii Supplementation as Probiotic on Productive Performance and Economic Efficiency of Growing Rabbits. Arab Universities Journal of Agricultural Sciences, 29(2), 795-800. https://doi.org/10.21608/ajs.2021.52876.1308
- Elmasry, A. M. A, Miranda, L. A., Mendoza, G., & Plata, F. X. (2021). Effect of Yeast Type and Dose on Growth Performance and Nutrient Digestibility of Growing Rabbits Fed Maize or Barley. Indian Journal of Animal Research. https://doi.org/10.18805/IJAR.B-1331
- Khan, K., Aziz, K., Khan, N. A., Khan, S., & Ayasan, T. (2022). Effect of enzyme and yeast-based feed additives on growth, nutrient digestibility, meat quality and intestinal morphology of fattening rabbits. Journal of the Hellenic Veterinary Medical Society, 72, 3511-3518. https://doi.org/10.12681/jhvms.29404
- EFSA (European Food Safety Authority) (2005). The Impact of the current housing and husbandry systems on the health and welfare of farmed domestic rabbits. EFSA Journal, 267, 1–31. https://doi.org/10.2903/j.efsa.2005.267
- Gidenne, T., Garreau, H., Drouilhet, L., Aubert, C., & Maertens, L. (2017). Improving feed efficiency in rabbit production, a review on nutritional, technico-economical, genetic and environmental aspects. Animal Feed Science and Technology, 225, 109-122.
- Maertens, L., & Gidenne, T. (2016). Feed efficiency in rabbit production: nutritional, technico-economical and environmental aspects. 11th World Rabbit Congress-June 15-18,2016-Qingdao-China, 337-352.
- Maj, D., Bieniek, J., Łapa, P., Sternstein, I. (2009). The effect of crossing New Zealand White with Californian rabbits on growth and slaughter traits. Archiv Tierzucht. 52. 205-211. https://doi.org/10.5194/aab-52-205-2009.
- Maertens L., De Groote G. (1992). Effect of a dietary supplementation of live yeast on the zootechnical performancfs of does and weanling rabbits Proceedings 5th World Rabbit Congress, 25-30 July 1992, Corvallis – USA, 1079-1086.